8 Best Python GUI Frameworks

Choosing the right Python GUI framework depends on your specific needs and the type of application you are developing.

Created by: Adeshola Bello /

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Otse Amorighoye

8 Best Python GUI Frameworks

Introduction to Python GUI Frameworks

Python's versatility is well-known, but did you know that it also excels in creating graphical user interfaces (GUIs)? From simple forms to complex dashboards, Python GUI frameworks can help you craft applications that are not only functional but also aesthetically pleasing. Whether you’re a beginner trying to get your first application off the ground or an experienced developer aiming to enhance your projects, the right GUI framework can make all the difference. This article will guide you through the best Python GUI frameworks, highlighting their strengths and use cases to help you choose the perfect tool for your needs. Ready to dive in? Let’s explore the top eight Python GUI frameworks that can elevate your projects to new heights!

1. Tkinter Overview


Tkinter is the de facto standard for Python GUI development. It’s included with Python, so you don’t need to install anything extra. Tkinter provides a robust set of tools for creating simple to moderately complex GUI applications.

Key Features

  • Ease of Use: Ideal for beginners due to its simplicity.

  • Cross-Platform: Works on Windows, macOS, and Linux.

  • Widget Variety: Offers a variety of standard widgets like buttons, labels, and text fields.

Use Cases

Tkinter is perfect for small to medium-sized applications, such as form-based data entry tools, simple games, and educational applications.

Strengths and Weaknesses

  • Strengths: Easy to learn, no extra installations required, good community support.

  • Weaknesses: Limited advanced features, not suitable for high-performance applications.

2. PyQt Overview


PyQt is a set of Python bindings for the Qt application framework. It offers a wide range of functionalities and is known for its versatility and performance.

Key Features

  • Rich Widget Set: Includes a vast array of widgets for building complex interfaces.

  • Cross-Platform: Supports Windows, macOS, Linux, iOS, and Android.

  • Comprehensive Documentation: Extensive resources and examples available.

Use Cases

PyQt is ideal for complex applications like professional software, multimedia tools, and enterprise-level systems.

Strengths and Weaknesses

  • Strengths: Powerful, feature-rich, excellent performance.

  • Weaknesses: Steeper learning curve, requires a commercial license for proprietary applications.

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3. Kivy Overview


Kivy is an open-source Python library for developing multitouch applications. It is designed to be easy to use and innovative, making it a great choice for modern, touch-based interfaces.

Key Features

  • Touch Support: Built-in support for multi-touch events.

  • Cross-Platform: Runs on Windows, macOS, Linux, Android, and iOS.

  • Graphics Engine: Leverages OpenGL for smooth, scalable graphics.

Use Cases

Kivy is perfect for developing mobile applications, interactive applications, and games.

Strengths and Weaknesses

  • Strengths: Modern design, touch and gesture support, active community.

  • Weaknesses: May not be suitable for traditional desktop applications, smaller widget set compared to others.

4. wxPython Overview


wxPython is a Python wrapper for the wxWidgets C++ library, allowing Python developers to create native-looking applications.

Key Features

  • Native Look and Feel: Provides a native look on different operating systems.

  • Comprehensive Widget Library: Offers a wide range of controls and widgets.

  • Cross-Platform: Supports Windows, macOS, and Linux.

Use Cases

wxPython is suitable for applications where a native appearance is critical, such as desktop software and system utilities.

Strengths and Weaknesses

  • Strengths: Native look and feel, extensive widget library, good performance.

  • Weaknesses: Can be more complex to set up, documentation can be lacking in certain areas.

5. PyGTK Overview


PyGTK is the Python binding for the GTK+ graphical user interface library. It is used primarily for creating applications that run on GNOME desktops.

Key Features

  • Integration with GNOME: Seamlessly integrates with GNOME desktop environments.

  • Rich Set of Widgets: Offers a wide range of widgets and tools.

  • Accessibility: Supports accessibility features for differently-abled users.

Use Cases

PyGTK is ideal for applications intended to run on Linux, particularly within the GNOME desktop environment.

Strengths and Weaknesses

  • Strengths: Excellent GNOME integration, accessibility support, rich widget set.

  • Weaknesses: Primarily Linux-focused, may require additional dependencies on other platforms.

6. PySide Overview


PySide is another set of Python bindings for the Qt application framework, similar to PyQt but with a more permissive license (LGPL).

Key Features

  • Comprehensive Toolkit: Access to all Qt features and functionalities.

  • Cross-Platform: Works on Windows, macOS, Linux, iOS, and Android.

  • LGPL License: More permissive for open-source and proprietary projects.

Use Cases

PySide is suitable for a wide range of applications, from desktop software to mobile apps, particularly when a more flexible licensing option is needed.

Strengths and Weaknesses

  • Strengths: Powerful, feature-rich, flexible licensing.

  • Weaknesses: Similar to PyQt, has a steeper learning curve and requires understanding of Qt.

7. Dear PyGui Overview


Dear PyGui is a fast and powerful GUI framework for Python, leveraging the Dear ImGui library. It is particularly suitable for applications requiring high performance and dynamic interfaces.

Key Features

  • Immediate Mode GUI: Provides an immediate mode GUI paradigm, which is fast and dynamic.

  • High Performance: Optimized for speed and efficiency.

  • Cross-Platform: Works on Windows, macOS, and Linux.

Use Cases

Dear PyGui is perfect for applications that require real-time updates, such as games, simulations, and data visualization tools.

Strengths and Weaknesses

  • Strengths: High performance, dynamic interfaces, modern design.

  • Weaknesses: Different programming paradigm, less traditional widget set.

8. Flexx Overview


Flexx is a Python library for creating desktop applications using web technologies. It allows you to write desktop applications that run in a browser or as standalone apps.

Key Features

  • Web Technologies: Uses HTML, CSS, and JavaScript for the GUI.

  • Reactive Programming: Supports reactive programming for dynamic interfaces.

  • Cross-Platform: Works on any platform with a modern web browser.

Use Cases

Flexx is ideal for developers who prefer web technologies and need to create applications that work seamlessly across different platforms.

Strengths and Weaknesses

  • Strengths: Leverages web technologies, cross-platform, modern and responsive design.

  • Weaknesses: Requires knowledge of web development, performance can vary depending on the browser.


Choosing the right Python GUI framework depends on your specific needs and the type of application you are developing. Here’s a quick recap to help you decide:

  • Tkinter: Best for beginners and simple applications.

  • PyQt: Ideal for complex, feature-rich applications.

  • Kivy: Perfect for touch-based and mobile applications.

  • wxPython: Great for native-looking desktop applications.

  • PyGTK: Excellent for GNOME desktop applications.

  • PySide: Similar to PyQt with a more flexible license.

  • Dear PyGui: Best for high-performance, dynamic interfaces.

  • Flexx: Perfect for those who prefer web technologies.

By understanding the strengths and weaknesses of each framework, you can make an informed decision and choose the best tool to bring your application to life.


Which Python GUI framework is best for beginners?

Tkinter is the best choice for beginners due to its simplicity and ease of use. It comes pre-installed with Python, making it easily accessible.

Can I create cross-platform applications with these frameworks?

Yes, all the mentioned frameworks support cross-platform development, allowing you to create applications that run on Windows, macOS, and Linux.

Do I need to know web development to use Flexx?

While not strictly necessary, knowledge of HTML, CSS, and JavaScript can be very helpful when using Flexx, as it leverages web technologies for building GUIs.

Is PyQt free to use?

PyQt is free for open-source projects under the GPL license. However, for proprietary applications, a commercial license is required.

Which framework should I use for mobile applications?

Kivy is the best choice for mobile applications due to its built-in support for multi-touch events and compatibility with Android and iOS platforms.

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